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Article

Exploiting tumor cell senescence in anticancer therapy

28 Feb 2014

Abstract excerpt

Cellular senescence is a physiological process of irreversible cell-cycle arrest that contributes to various physiological and pathological processes of aging. Whereas replicative senescence is associated with telomere attrition after repeated cell division, stress-induced premature senescence occurs in response to aberrant oncogenic signaling, oxidative stress, and DNA damage which is independent of telomere...

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Share to Advanced biosensing and bioanalysis techniques
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Share to Telomeres, Telomerase, and Senescence

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Identifiers

PMID: 24411464
DOI: 10.5483/bmbrep.2014.47.2.005

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