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Article

Independent Associated SNPs at SORCS3 and Its Protein Interactors for Multiple Brain-Related Disorders and Traits.

Genes - 14 Feb 2023

Kamran Muhammad, Laighneach Aodán, Bibi Farhana, Donohoe Gary, Ahmed Naveed, Rehman Asim Ur, Morris Derek W

Abstract excerpt

Sortilin-related vacuolar protein sorting 10 (VPS10) domain containing receptor 3 (SORCS3) is a neuron-specific transmembrane protein involved in the trafficking of proteins between intracellular vesicles and the plasma membrane. Genetic variation at SORCS3 is associated with multiple neuropsychiatric disorders and behavioural phenotypes. Here, we undertake a systematic search of published genome-wide association...

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Brain
Brain Diseases
Genome-Wide Association Study
Nerve Tissue Proteins
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Receptors, Cell Surface

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PMID: 36833409
DOI: 10.3390/genes14020482
PMCID: PMC9956385

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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