Article
Detecting Melanocortin 1 Receptor Gene's SNPs by CRISPR/enAsCas12a.
Genes - 2 Feb 2023
Yang Wei, Tao Dagang, Xu Bingrong, Zheng Yueting, Zhao Shuhong
Abstract excerpt
Beyond its powerful genome-editing capabilities, the CRISPR/Cas system has opened up a new era of molecular diagnostics due to its highly specific base recognition and trans-cleavage activity. However, most CRISPR/Cas detection systems are mainly used to detect nucleic acids of bacteria or viruses, while the application of single nucleotide polymorphism (SNP) detection is limited. The MC1R SNPs were investigated...
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