Article
Effects of Wnt10a and Wnt10b Double Mutations on Tooth Development.
Genes - 28 Jan 2023
Yoshinaga Kaoru, Yasue Akihiro, Mitsui Silvia Naomi, Minegishi Yoshiyuki, Oyadomari Seiichi, Imoto Issei, Tanaka Eiji
Abstract excerpt
WNT molecules are the regulators of various biological functions, including body axis formation, organ development, and cell proliferation and differentiation. WNTs have been extensively studied as causative genes for an array of diseases. WNT10A and WNT10B, which are considered to be genes of the same origin, have been identified as causative genes for tooth deficiency in humans. However, the disrupted mutant of...
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