Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Abnormal primary and permanent dentitions with ectodermal symptoms predict WNT10A deficiency.

BMC medical genetics - 24 Nov 2016

Bergendal Birgitta, Norderyd Johanna, Zhou Xiaolei, Klar Joakim, Dahl Niklas

Abstract excerpt

BACKGROUND: The WNT10A protein is critical for the development of ectodermal appendages. Variants in the WNT10A gene may be associated with a spectrum of ectodermal abnormalities including extensive tooth agenesis. METHODS: In seven patients with severe tooth agenesis we identified anomalies in primary dentition and additional ectodermal symptoms, and assessed WNT10A mutations by genetic analysis. RESULTS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anodontia
Share to Child
Share to Dental Enamel Hypoplasia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ectodermal Dysplasia

Share to Homozygote

Share to Tooth Abnormalities

Share to Tooth, Deciduous

Share to Wnt Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 27881089
DOI: 10.1186/s12881-016-0349-4
PMCID: PMC5122154

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Abnormal primary and permanent dentitions with ectodermal symptoms predict WNT10A deficiency.PMID 27881089Read ↗

Genotypic and phenotypic correlations in tooth agenesis: insights from WNT10A and EDA mutations in syndromic and non-syndromic forms.Semantic proximity Read ↗

Molecular Basis and Clinical Spectrum of WNT10A-Related Oligodontia.Semantic proximity Read ↗

WNT10A, dermatology and dentistry.Semantic proximity Read ↗

Mutations in WNT10A are present in more than half of isolated hypodontia cases.Semantic proximity Read ↗

Dental and extra-oral clinical features in 41 patients with WNT10A gene mutations: A multicentric genotype-phenotype study.Semantic proximity Read ↗

Mutations in WNT10A are frequently involved in oligodontia associated with minor signs of ectodermal dysplasia.Semantic proximity Read ↗

WNT10A variants are associated with non-syndromic tooth agenesis in the general population.Semantic proximity Read ↗

The WNT10A gene in ectodermal dysplasias and selective tooth agenesis.Semantic proximity Read ↗

Distinct impacts of bi‐allelic WNT10A mutations on the permanent and primary dentitions in odonto‐onycho‐dermal dysplasiaSemantic proximity Read ↗

Compound heterozygous WNT10A missense variations exacerbated the tooth agenesis caused by hypohidrotic ectodermal dysplasia.Semantic proximity Read ↗

Patterns of Dental Agenesis Highlight the Nature of the Causative Mutated Genes.Semantic proximity Read ↗

A novel WNT10A mutation causes non-syndromic hypodontia in an Egyptian family.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.