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Flow Cytometric Characterization of Human Antigen-Reactive T-Helper Cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Saggau Carina, Scheffold Alexander, Bacher Petra

Abstract excerpt

The detection and functional characterization of antigen-reactive T helper (Th) cells has been challenging due to their low frequency and functional heterogeneity. Antigen-reactive T cell enrichment (ARTE) allows the in-depth characterization of antigen-specific Th lymphocytes as a prerequisite for better understanding the role of adaptive immune responses in health and disease. ARTE is based on detection of the...

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PMID: 33928550
DOI: 10.1007/978-1-0716-1311-5_12

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