Article
Features and clinical implications of hepatitis B virus genotypes and mutations in basal core promoter/precore region in 507 Chinese patients with acute and chronic hepatitis B.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Mar 2010
Liu Yan, Zhong Yanwei, Zou Zhengsheng, Xu Zhihui, Li Baosen, Ren Xiaoqiang, Bai Siyu, Wang Lin, Li Xiaodong, Dai Jiuzeng, Wang Yao, Mao Panyong, Xu Dongping
Abstract excerpt
BACKGROUND: The association of hepatitis B virus (HBV) genotypes and basal core promoter (BCP) and precore (PC) mutations with the clinical characteristics is increasingly recognized. OBJECTIVE: To investigate virologic features and clinical implications of HBV genotypes, BCP and PC mutations between large-size patients with acute hepatitis B (AHB) and chronic hepatitis B (CHB). STUDY DESIGN: One hundred and...
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