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Article

Deep sequencing of hepatitis B virus basal core promoter and precore mutants in HBeAg-positive chronic hepatitis B patients.

Scientific reports - 9 Dec 2015

Yan Linlin, Zhang Henghui, Ma Hui, Liu Di, Li Wei, Kang Yulin, Yang Ruifeng, Wang Jianghua, He Gaixia, Xie Xingwang, Wang Hao, Wei Lai, Lu Zuhong, Shao Qixiang, Chen Hongsong

Abstract excerpt

Mutants in the basal core promoter (BCP) and precore (PC) regions of hepatitis B virus (HBV) genome are associated with the progression of chronic hepatitis B (CHB) infection. However, quasispecies characteristics of naturally occurring mutants in those regions in HBeAg-positive CHB patients has not been well described, partly limited by quantitative assay. This study aimed to develop an Ion Torrent deep...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26647737
DOI: 10.1038/srep17950
PMCID: PMC4673698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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