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Article

Vitamin D attenuates elevated oxidative DNA damage in scleroderma patients with organ involvement: A prospective study.

The Journal of steroid biochemistry and molecular biology - 1 May 2023

Dal-Bekar Nazlı Ecem, İşlekel Gül Hüray, Köken-Avşar Aydan, Yarkan-Tuğsal Handan, Tuna Gamze, Zengin Berrin, Birlik Ahmet Merih

Abstract excerpt

Scleroderma is a rare autoimmune disease characterized by progressive fibrosis of the skin and internal organs. Oxidative damage to macromolecules has been reported to occur in scleroderma. Among the macromolecular damages, oxidative DNA damage is a sensitive and cumulative marker of oxidative stress and is of particular interest because of its cytotoxic and mutagenic effects. Vitamin D supplementation is an...

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PMID: 36813139
DOI: 10.1016/j.jsbmb.2023.106273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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