Article
[Clonal Hematopoiesis and Solid Cancer].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Feb 2023
Sakata-Yanagimoto Mamiko, Makishima Kenichi, Suehara Yasuhito
Abstract excerpt
In the hematopoietic system of healthy individuals, a phenomenon called clonal hematopoiesis, in which cells acquired somatic mutations are replaced with aging, has been discovered. The frequency of clonal hematopoiesis is higher in patients with solid tumors, than normal individuals. In addition, it is thought that infiltration of inflammatory cells with somatic mutations into cancer tissues may change the tumor...
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