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Multifaceted genome-wide study identifies novel regulatory loci in SLC22A11 and ZNF45 for body mass index in Indians.

Molecular genetics and genomics : MGG - 1 Jul 2020

Giri Anil K, Prasad Gauri, Bandesh Khushdeep, Parekatt Vaisak, Mahajan Anubha, Banerjee Priyanka, Kauser Yasmeen, Chakraborty Shraddha, Rajashekar Donaka, Sharma Abhay, Mathur Sandeep Kumar, Basu Analabha, McCarthy Mark I, Tandon Nikhil, Bharadwaj Dwaipayan

Abstract excerpt

Obesity, a risk factor for multiple diseases (e.g. diabetes, hypertension, cancers) originates through complex interactions between genes and prevailing environment (food habit and lifestyle) that varies across populations. Indians exhibit a unique obesity phenotype with high abdominal adiposity for a given body weight compared to matched white populations suggesting presence of population-specific genetic and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Regulatory Sequences, Nucleic Acid

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PMID: 32363570
DOI: 10.1007/s00438-020-01678-6

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