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The Negative Correlation Between TNBC Mutation Frequency and Immune Function: Is Immune Involvement in Regulating Mutations?

2021-04-08

Abstract excerpt

<title>Abstract</title> <p><bold>Introduction: </bold>Triple-negative breast cancer (TNBC) is a highly specific disease. It has been reported that TNBC has a higher gene mutation frequency than non-triple-negative breast cancer (nTNBC). Most TNBC gene mutation studies focus on BRCA1, BRCA2, TP53 and other highly mutated genes. However, few studies on extensive somatic mutations of TNBC have been conducted. Explor...

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Literature Corpus work
1fa9e76e-ca27-51ba-948d-cb18f585d89a
DOI
10.21203/rs.3.rs-393949/v1
Open publication

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