Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic analysis of tumor mutation burden and immune infiltration in hepatocellular carcinoma based on TCGA data.

Aging - 4 Apr 2021

Liu Shaoqing, Tang Qianjie, Huang Jianwen, Zhan Meixiao, Zhao Wei, Yang Xiangyu, Li Yong, Qiu Lige, Zhang Fujun, Lu Ligong, He Xu

Abstract excerpt

In order to explore the prognosis of tumor mutation burden (TMB) and the relationship with tumor infiltrating immune cells in hepatocellular carcinoma (HCC), we downloaded somatic mutation data and transcriptome profiles of 376 HCC patients from The Cancer Genome Atlas (TCGA) cohort. We divided the samples into high-TMB and low-TMB groups. A higher TMB level indicated improved overall survival (OS) and was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Datasets as Topic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Kaplan-Meier Estimate

Share to Liver Neoplasms

Share to Neoplasm Recurrence, Local

Share to ROC Curve

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 33820866
DOI: 10.18632/aging.202811
PMCID: PMC8109113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic analysis of tumor mutation burden and immune infiltration in hepatocellular carcinoma based on TCGA data.PMID 33820866Read ↗

A novel panel based on immune infiltration and tumor mutational burden for prognostic prediction in hepatocellular carcinoma.Semantic proximity Read ↗

A novel panel based on Immune infiltration and tumor mutational burden for prognostic prediction in hepatocellular carcinomaSemantic proximity Read ↗

Comprehensive analysis of tumour mutation burden and the immune microenvironment in hepatocellular carcinoma.Semantic proximity Read ↗

Identification of Tumor Mutation Burden and Immune Infiltrates in Hepatocellular Carcinoma Based on Multi-Omics AnalysisSemantic proximity Read ↗

Identification of Tumor Mutation Burden and Immune Infiltrates in Hepatocellular Carcinoma Based on Multi-Omics AnalysisSemantic proximity Read ↗

Multi-omics analysis reveals prognostic value of tumor mutation burden in hepatocellular carcinomaSemantic proximity Read ↗

Identification of Tumor Mutation Burden and Immune Infiltrates in Hepatocellular Carcinoma Based on Multi-Omics AnalysisSemantic proximity Read ↗

Integrated Analysis of Tumor Mutation Burden and Immune Infiltrates in Hepatocellular CarcinomaSemantic proximity Read ↗

Exploration of Key Genes Combining with Immune Infiltration Level andTumor Mutational Burden in Hepatocellular Carcinoma.Semantic proximity Read ↗

Identification of a seven-gene signature predicting clinical outcome of liver cancer based on tumor mutational burdenSemantic proximity Read ↗

A Prognostic Model of 15 Immune-Related Gene Pairs Associated With Tumor Mutation Burden for Hepatocellular CarcinomaSemantic proximity Read ↗

Exploration of Key Genes Combining with Immune Infiltration Level and Tumor Mutational Burden in Hepatocellular CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.