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Article

LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway.

Oncology reports - 1 Mar 2023

Han Sijia, Jin Xueying, Hu Tianyu, Chi Feng

Abstract excerpt

Breast cancer remains the most common malignancy and the leading cause of cancer‑associated mortality in women worldwide. Lysosomal protein transmembrane 5 (LAPTM5), a lysosomal membrane protein, plays an important role in several human malignancies. However, the biological functions and mechanism of LAPTM5 in breast cancer remain unclear. In the present study, the potential tumor‑promoting effect of LAPTM5 was...

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Identifiers

PMID: 36799186
DOI: 10.3892/or.2023.8497
PMCID: PMC9942259

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