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IL-17 genetic and immunophenotypic evaluation in chronic graft-versus-host disease.

Mediators of inflammation - 1 Jan 2014

Resende Renata Gonçalves, Correia-Silva Jeane de Fátima, Silva Tarcília Aparecida, Salomão Ulisses Eliezer, Marques-Silva Luciano, Vieira Érica Leandro Marciano, Dutra Walderez Ornelas, Gomez Ricardo Santiago

Abstract excerpt

Although interleukin-17 (IL-17) is a recently discovered cytokine associated with several autoimmune diseases, its role in the pathogenesis of chronic graft-versus-host disease (cGVHD) was not established yet. The objective of this study was to investigate the association of IL17A and IL17F genes polymorphisms and IL-17A and IL-17F levels with cGVHD. IL-17A expression was also investigated in CD4(+) T cells of...

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Identifiers

PMID: 25136146
DOI: 10.1155/2014/571231
PMCID: PMC4129170

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Source receipt: pubmed, retrieved 7 Sept 2026.

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