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Associations of IL-17 and IL-17 receptor polymorphisms with Behçet's disease in Denizli Province of Turkey.

Immunologic research - 1 Aug 2023

Arıkan Sanem, Öztürk Onur, Duygulu Şeniz, Atalay Erol Ömer, Atalay Ayfer

Abstract excerpt

Although the etiopathogenesis of Behçet's disease is not known, studies conducted in different populations show that it is a multifactorial disease that is thought to develop as a result of the interaction of environmental and genetic factors. IL-17 is thought to induce the neutrophilic inflammation and the tissue damage mediated by immune response in patients. Polymorphisms in the gene region encoding IL-17 and...

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PMID: 36701075
DOI: 10.1007/s12026-023-09363-7

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