Two CRISPR/Cas12a-based methods for fast and accurate detection of single-base mutations.

Abstract excerpt

Current single-base mutation detection approaches are time-consuming, labor-intensive, and costly. This highlights the critical need for speedy and accurate technology capable of detecting single-base alterations. Using clustered regularly interspaced short palindromic repeats/associated protein...

Topics

• CRISPR-Cas Systems
• Proteolysis
• Mutation
• Recombinases
• DNA Primers