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Article

Prognostic and Therapeutic Potential Implications of Genetic Variability in Prostaglandin E2 Pathway Genes in Rectal Cancer.

Anticancer research - 1 Jan 2017

Santos Marisa D, Silva Cristina, Rocha Anabela, Nogueira Carlos, Castro-Poças Fernando, Araujo António, Matos Eduarda, Pereira Carina, Medeiros Rui, Lopes Carlos

Abstract excerpt

AIM: To evaluate the prognostic significance and potential therapeutic implication of genetic variability in prostaglandin E2 pathway genes in patients with locally advanced rectal cancer (LARC) treated with neoadjuvant chemoradiotherapy (nCRT) followed by surgery. MATERIALS AND METHODS: This cohort study included 167 patients with LARC, treated with nCRT followed by surgery. A total of 61 single nucleotide...

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Identifiers

PMID: 28011504
DOI: 10.21873/anticanres.11319

Genes

ABCC4
TRG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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