Article
Impact of Pattern Recognition Receptors on the Prognosis of Chemotherapy-treated Rectal Cancer Patients.
In vivo (Athens, Greece) - 1 Jan 2000
Chang Chia-Lin, Huang Kevin Chih-Yang, Chen Tsung-Wei, Chen William Tzu-Liang, Ke Tao-Wei, Liou Yih-Farng, Chao K S Clifford, Chiang Shu-Fen
Abstract excerpt
BACKGROUND/AIM: Chemotherapeutic drugs or radiation can cause immunogenic cell death (ICD) and damage-associated molecular pattern (DAMP) release to activate pattern recognition receptor (PRR) in immune cells. Several PRRs bridge innate immunity and adaptive immunity and are implicated in the anticancer immune response. However, single nucleotide polymorphisms (SNPs) in PRRs are associated with chemotherapeutic...
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