Article
Association between genetic polymorphisms in the promoters of let-7 and risk of cervical squamous cell carcinoma.
Gene - 5 Feb 2018
Liu Jing, Ni Shanshan
Abstract excerpt
Numerous reports showed low levels of let-7 family in cervical cancer, acting as tumor suppressors by regulating multiple target genes. Genetic variants in the promoter of miRNA have been reported to influence individuals' susceptibility to human diseases. We aimed to investigate the association of rs10877887 and rs13293512 polymorphisms in the promoters of let-7 with risk of cervical squamous cell carcinoma...
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