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Article

Genetic variants in the promoters of let-7 family are associated with an increased risk of major depressive disorder.

Journal of affective disorders - 1 Sept 2015

Liang Yundan, Zhao Gaofeng, Sun Ruifen, Mao Yuanyi, Li Gangqin, Chen Xueyan, Gao Linbo, Hu Zeqing

Abstract excerpt

BACKGROUND: Let-7 family plays a critical role in the pathogenesis of major depressive disorder (MDD). Genetic polymorphisms in the promoters of miRNA may influence individual׳s susceptibility to diseases. The purpose of this study was to investigate the association between rs10877887 and rs13293512 polymorphisms in the promoters of let-7 family and the risk of MDD. METHOD: Polymerase chain reaction-restriction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26047307
DOI: 10.1016/j.jad.2015.04.035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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