A single nucleotide polymorphism in the promoter region (rs10877887) of let-7 is associated with hepatocellular carcinoma in a Chinese population.

doi:10.4238/gmr.15027661

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Article

A single nucleotide polymorphism in the promoter region (rs10877887) of let-7 is associated with hepatocellular carcinoma in a Chinese population.

Genetics and molecular research : GMR - 13 May 2016

Sui Z Y, Li J, Cheng G L, Wang S F

Abstract excerpt

Hepatocellular carcinoma (HCC) is a complex polygenic disease whose development is dependent on many genetic factors. The let-7 family, an important and widely studied microRNA family, has been shown to play an important role in the initiation and progression of HCC. In this study, we examined the possible associations between single-nucleotide polymorphisms in the promoter region of the let-7 family (rs10877887)...

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PMID: 27323017
DOI: 10.4238/gmr.15027661

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