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Article

Effects of mutant huntingtin in oxytocin neurons on non-motor features of Huntington's disease.

Neuropathology and applied neurobiology - 1 Apr 2023

Bergh Sofia, Gabery Sanaz, Tonetto Simone, Kirik Deniz, Petersén Åsa, Cheong Rachel Y

Abstract excerpt

BACKGROUND: Early non-motor features including anxiety, depression and altered social cognition are present in Huntington's disease (HD). The underlying neurobiological mechanisms are not known. Oxytocin (OXT) is involved in the regulation of emotion, social cognition and metabolism, and our previous work showed that the OXT system is affected early in HD. The aim of the study was to investigate the potential...

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PMID: 36776123
DOI: 10.1111/nan.12891

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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