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Cancer Stem Cell and Aggressiveness Traits Are Promoted by Stable Endothelin-Converting Enzyme-1c in Glioblastoma Cells.

Cells - 3 Feb 2023

Niechi Ignacio, Erices José I, Carrillo-Beltrán Diego, Uribe-Ojeda Atenea, Torres Ángelo, Rocha José Dellis, Uribe Daniel, Toro María A, Villalobos-Nova Karla, Gaete-Ramírez Belén, Mingo Gabriel, Owen Gareth I, Varas-Godoy Manuel, Jara Lilian, Aguayo Francisco, Burzio Verónica A, Quezada-Monrás Claudia, Tapia Julio C

Abstract excerpt

Glioblastoma (GBM) is the most common and aggressive type of brain tumor due to its elevated recurrence following treatments. This is mainly mediated by a subpopulation of cells with stemness traits termed glioblastoma stem-like cells (GSCs), which are extremely resistant to anti-neoplastic drugs. Thus, an advancement in the understanding of the molecular processes underlying GSC occurrence should contribute...

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Identifiers

PMID: 36766848
DOI: 10.3390/cells12030506
PMCID: PMC9914402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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