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Article

The heterogeneity of cancer stem-like cells at the invasive front

13 Feb 2017

Abstract excerpt

Cancer stem-like cells exhibit the multi-functional roles to survive and persist for a long period in the minimal residual disease after the conventional anti-cancer treatments. Cancer stem-like cells of solid malignant tumors which highly express CD44v8-10, the variant isoform of CD44 generated by alternative splicing, has a resistance to redox stress by the robust production of glutathione mediated by...

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PMID: 28289330
DOI: 10.1186/s12935-017-0393-y

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