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Article

Molecular characteristics of single patient-derived glioma stem-like cells from primary and recurrent glioblastoma.

Anti-cancer drugs - 1 Jan 2022

Shi Jia, Dong Xuchen, Han Wei, Zhou Peng, Liu Liang, Wang Haiyang, Jiang Qianqian, Li Haoran, Cheng Shan, Li Suwen, Yuan Jiaqi, Qian Zhiyuan, Dong Jun

Abstract excerpt

Glioblastoma has high recurrence, while the sensitivity of recurrent glioblastoma to chemotherapy is lower than that of primary glioblastoma. Moreover, there is no standardized treatment for recurrent glioblastoma. Unfortunately, the biological mechanism of recurrent glioblastoma is still unclear, and there are few related studies. We compared the phenotypes of clinical glioblastoma specimens, in-vitro cultured...

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Identifiers

PMID: 34419956
DOI: 10.1097/CAD.0000000000001217
PMCID: PMC8670354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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