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Article

Oncogenic activity of SOX1 in glioblastoma

20 Apr 2017

Abstract excerpt

Glioblastoma remains the most common and deadliest type of brain tumor and contains a population of self-renewing, highly tumorigenic glioma stem cells (GSCs), which contributes to tumor initiation and treatment resistance. Developmental programs participating in tissue development and homeostasis re-emerge in GSCs, supporting the development and progression of glioblastoma. SOX1 plays an important role in neural...

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PMID: 28425506
DOI: 10.1038/srep46575

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