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Article

Genetic variants in the PIWI-piRNA pathway gene DCP1A predict melanoma disease-specific survival.

International journal of cancer - 15 Dec 2016

Zhang Weikang, Liu Hongliang, Yin Jieyun, Wu Wenting, Zhu Dakai, Amos Christopher I, Fang Shenying, Lee Jeffrey E, Li Yi, Han Jiali, Wei Qingyi

Abstract excerpt

The Piwi-piRNA pathway is important for germ cell maintenance, genome integrity, DNA methylation and retrotransposon control and thus may be involved in cancer development. In this study, we comprehensively analyzed prognostic roles of 3,116 common SNPs in PIWI-piRNA pathway genes in melanoma disease-specific survival. A published genome-wide association study (GWAS) by The University of Texas M.D. Anderson...

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Identifiers

PMID: 27578485
DOI: 10.1002/ijc.30409
PMCID: PMC5282969

Genes

PIWIL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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