Article
Association of PD-1 polymorphisms with the risk and prognosis of lung adenocarcinoma in the northeastern Chinese Han population.
BMC medical genetics - 12 Nov 2019
Huang Kun, Hu Erqiang, Li Wan, Lv Junjie, He Yuehan, Deng Gui, Xiao Jinling, Yang Chengcheng, Zhao Xinyu, Chen Lina, Wang Xinyan
Abstract excerpt
BACKGROUND: Lung cancer is a leading cause of death from cancer worldwide, especially non-small cell lung cancer (NSCLC). The marker of progression in lung adenocarcinoma, the main type of NSCLC, has been rarely studied. Programmed death 1 (PD-1) is an effective drug target for the treatment of NSCLC. Our study aimed to examine the PD-1 role in the disease process. The study of the effect of polymorphisms on the...
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