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Article

Alzheimer's disease phenotypes show different sleep architecture.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Aug 2023

Falgàs Neus, Walsh Christine M, Yack Leslie, Simon Alexander J, Allen Isabel E, Kramer Joel H, Rosen Howard J, Joie Renaud La, Rabinovici Gil, Miller Bruce, Spina Salvatore, Seeley William W, Ranasinghe Kamalini, Vossel Keith, Neylan Thomas C, Grinberg Lea T

Abstract excerpt

INTRODUCTION: Sleep-wake disturbances are a prominent feature of Alzheimer's disease (AD). Atypical (non-amnestic) AD syndromes have different patterns of cortical vulnerability to AD. We hypothesized that atypical AD also shows differential vulnerability in subcortical nuclei that will manifest as different patterns of sleep dysfunction. METHODS: Overnight electroencephalography monitoring was performed on 48...

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Identifiers

PMID: 36749893
DOI: 10.1002/alz.12963
PMCID: PMC10404632

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