Article
Sleep spindle architecture associated with distinct clinical phenotypes in older adults at risk for dementia.
Molecular psychiatry - 1 Feb 2024
Orlando Isabella F, O'Callaghan Claire, Lam Aaron, McKinnon Andrew C, Tan Joshua B C, Michaelian Johannes C, Kong Shawn D X, D'Rozario Angela L, Naismith Sharon L
Abstract excerpt
Sleep spindles are a hallmark of non-REM sleep and play a fundamental role in memory consolidation. Alterations in these spindles are emerging as sensitive biomarkers for neurodegenerative diseases of ageing. Understanding the clinical presentations associated with spindle alterations may help to elucidate the functional role of these distinct electroencephalographic oscillations and the pathophysiology of sleep...
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