Article
Plasma circulating tumor DNA profiling in patients with chemo-refractory germ cell tumors.
International journal of urology : official journal of the Japanese Urological Association - 1 May 2023
Sakka Shotaro, Kandori Shuya, Kawai Koji, Kojima Takahiro, Nitta Satoshi, Chihara Ichiro, Nagumo Yoshiyuki, Kawahara Takashi, Mathis Bryan J, Ishihara Megumi, Shinohara Nobuo, Kishida Takeshi, Ukimura Osamu, Nishimura Kazuo, Kobayashi Yasuyuki, Nishiyama Hiroyuki
Abstract excerpt
OBJECTIVES: Molecular analysis of tumor tissues has been extensively analyzed in germ cell tumors. However, genetic analysis of plasma circulating tumor DNA has been limited. Our objective was to analyze genetic alterations in circulating tumor DNA as well as its impact on prognosis in patients with chemo-refractory germ cell tumors. METHODS: We included 13 patients with chemo-refractory germ cell tumors who...
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