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Liquid biopsy-based comprehensive gene mutation profiling for gynecological cancer using CAncer Personalized Profiling by deep Sequencing

18 Jul 2019

Abstract excerpt

Liquid biopsies of circulating tumor DNA (ctDNA) have recently been used as a non-invasive diagnostic tool for detecting tumor-specific mutations. We present a study of ctDNA liquid biopsies in gynecological cancer using an ultrasensitive next-generation sequencing-based method for ctDNA detection named CAncer Personalized Profiling by deep Sequencing (CAPP-Seq). We performed CAPP-Seq with plasma-ctDNA obtained...

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Cancer Genomics and Diagnostics
Molecular Biology Techniques and Applications
Renal cell carcinoma treatment

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31320709
DOI: 10.1038/s41598-019-47030-w

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