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SH-SY5Y Cell Line In Vitro Models for Parkinson Disease Research—Old Practice for New Trends

16 Jan 2023

Abstract excerpt

The SH-SY5Y cell line is a simple and inexpensive in vitro experimental model for studying Parkinson disease (PD). This experimental model is a useful tool for elucidating pathophysiological mechanisms of PD and in the development of new pharmacological therapies. In this review, we aim to summarize current protocols for SH-SY5Y cell culturing and differentiation and PD experimental designs derived from the...

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PMID: 36722247
DOI: 10.31083/j.jin2201020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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