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Quantitative Characterization of Phenotypical Markers After Differentiation of SH-SY5Y Cells.

CNS & neurological disorders drug targets - 1 Jan 2020

Ducray Angélique D, Wiedmer Linda, Herren Fabienne, Widmer Hans Rudolf, Mevissen Meike

Abstract excerpt

BACKGROUND: The human neuroblastoma cell line, SH-SY5Y, has been widely used in neuroscience research, especially in studies related to Parkinson's disease. However, differences between clones have been demonstrated, highlighting the importance to characterize the properties of this cell line carefully. OBJECTIVE: The aim of this study was to characterize the phenotype of undifferentiated and differentiated...

Topics

Biomarkers
Cell Differentiation
Cell Line, Tumor
Cholinergic Neurons
Dopamine
Dopaminergic Neurons
Humans
Neuroblastoma
Parkinson Disease
Phenotype
Signal Transduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tretinoin

Tyrosine 3-Monooxygenase

Up-Regulation

Source

Identifiers

PMID: 32640966
DOI: 10.2174/1871527319666200708132716

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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