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Robust In Vitro Models for Studying Parkinson’s Disease? LUHMES Cells and SH-SH5Y Cells

6 Dec 2024

Abstract excerpt

As our population ages, there is an increased unmet clinical need surrounding neurodegenerative diseases such as Parkinson's disease (PD). To tackle this ever-increasing problem, we must ensure that the cell models that we use to develop therapeutics in vitro are robust, reliable, and replicable. In this study, we compared SH-SY5Y cells with LUHMES cells in response to 6-Hydroxydopamine (6OHDA) and...

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PMID: 39684831
DOI: 10.3390/ijms252313122

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