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Article

Association of KIR2DL5, KIR2DS5, and KIR2DS1 allelic variation and atopic dermatitis.

Scientific reports - 31 Jan 2023

Margolis David J, Mitra Nandita, Hoffstad Ole J, Berna Ronald, Kim Brian S, Chopra Abha, Phillips Elizabeth J

Abstract excerpt

Natural killer cells (NK) have been associated with the pathophysiology of atopic dermatitis (AD). NK function is regulated by killer cell Ig-like receptor family (KIR) receptors that interact with HLA ligands. The study goal was to focus on allelic variation in genes KIR2DL5, KIR2DS5, and KIR2DS1 with respect to AD. This was a case-control study of individuals with (n = 313) and without (n = 176) AD....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36720995
DOI: 10.1038/s41598-023-28847-y
PMCID: PMC9889380

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