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Article

The von Hippel-Lindau Tumor Suppressor Gene Mutations Modulate Lipocalin-2 Expression in Ferroptotic-Inflammatory Pathways.

Oxidative medicine and cellular longevity - 1 Jan 2023

Kuo Chan-Yen, Hsieh Po-Chun, Chiu Valeria, Lan Chou-Chin, Lu Kuo-Cheng

Abstract excerpt

A previous study of an animal model with tumor suppressor gene von Hippel-Lindau (VHL) conditional knockdown suggested that tissue inflammation and fibrosis play important roles in the development of clear-cell renal cell carcinoma (ccRCC), which is consistent with the epidemiological evidence linking inflammatory kidney disease and renal cancer. Ferroptosis and inflammation have been linked in a recent study,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36718277
DOI: 10.1155/2023/7736638
PMCID: PMC9884170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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