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Article

EGR1 Promotes Erastin-induced Ferroptosis Through Activating Nrf2-HMOX1 Signaling Pathway in Breast Cancer Cells

1 Jan 2024

Abstract excerpt

The expression of EGR1 is downregulated in BC, which is correlated with poor prognosis of BC patients. EGR1 suppresses the proliferation of BC cells and facilitates erastin-induced ferroptosis by activating Nrf2-HMOX1 signaling pathway in BC cells.

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PMID: 39006084
DOI: 10.7150/jca.95328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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