Article
Determination of the inhibitory activity and biological half-live of soluble CD83: comparison of wild type and mutant isoforms.
Immunobiology - 1 Jan 2006
Zinser Elisabeth, Lechmann Matthias, Golka Antje, Hock Barry, Steinkasserer Alexander
Abstract excerpt
A soluble form of CD83 ("sCD83") has been shown to block DC-mediated T cell stimulation in vitro and an immunosuppressive role has also been shown in vivo using an experimental-autoimmune-encephalomyelits (EAE) model. Using recombinant mutational analyses, recently, we could show that sCD83 forms...
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