Visualizing Cathepsin K‐Cre Expression at the Single‐Cell Level with GFP Reporters

Abstract excerpt

ABSTRACT The Cre/lox system is a fundamental tool for functional genomic studies, and a number of Cre lines have been generated to target genes of interest spatially and temporally in defined cells or tissues; this approach has greatly expanded our knowledge of gene functions. However, the limitations of this system have recently been recognized, and we must address the challenge of so‐called...

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