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Article

Characterization of Mouse Cathepsin K Gene, the Gene Promoter, and the Gene Expression

1 Apr 1999

Abstract excerpt

Cathepsin K, a lysosomal cysteine protease, is abundantly and selectively expressed in osteoclasts and has a specialized role in osteoclast-mediated bone resorption. In contrast to function studies, transcription regulation of cathepsin K remains largely unknown. In this study, the gene encoding mouse cathepsin K and the promoter have been isolated and completely sequenced. In addition, the temporal and spatial...

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Identifiers

PMID: 10234569
DOI: 10.1359/jbmr.1999.14.4.487

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