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Article

Gut Microbiome Composition and Metabolic Capacity Differ by FUT2 Secretor Status in Exclusively Breastfed Infants.

Nutrients - 16 Jan 2023

Thorman Alexander W, Adkins Grace, Conrey Shannon C, Burrell Allison R, Yu Ying, White Brendon, Burke Rachel, Haslam David, Payne Daniel C, Staat Mary A, Morrow Ardythe L, Newburg David S

Abstract excerpt

A major polymorphism in the fucosyltransferase2 (FUT2) gene influences risk of multiple gut diseases, but its impact on the microbiome of breastfed infants was unknown. In individuals with an active FUT2 enzyme (“secretors”), the intestinal mucosa is abundantly fucosylated, providing mutualist bacteria with a rich endogenous source of fucose. Non-secretors comprise approximately one-fifth of the population, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36678342
DOI: 10.3390/nu15020471
PMCID: PMC9866411

Genes

FUT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Gut Microbiome Composition and Metabolic Capacity Differ by FUT2 Secretor Status in Exclusively Breastfed Infants.PMID 36678342Read ↗

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