Article
FUT2 genotype and secretory status are not associated with fecal microbial composition and inferred function in healthy subjects.
Gut microbes - 4 Jul 2018
Turpin Williams, Bedrani Larbi, Espin-Garcia Osvaldo, Xu Wei, Silverberg Mark S, Smith Michelle I, Guttman David S, Griffiths Anne, Moayyedi Paul, Panaccione Remo, Huynh Hien, Steinhart Hillary, Aumais Guy, Shestopaloff Konstantin, Dieleman Levinus A, Turner Dan, Paterson Andrew D, Croitoru Kenneth
Abstract excerpt
Heritability analysis of the microbiota has demonstrated the importance of host genotype in defining the human microbiota. The alpha (1,2)-fucosyltransferase 2 encoded by FUT2 is involved in the formation of the H antigen and the SNP, rs601338 is associated with ABO histo-blood group antigen secretion in the intestinal mucosa. Previous studies have provided non replicated results for the association of this...
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