Article
Fucosyltransferase 2 non-secretor and low secretor status predicts severe outcomes in premature infants.
The Journal of pediatrics - 1 May 2011
Morrow Ardythe L, Meinzen-Derr Jareen, Huang Pengwei, Schibler Kurt R, Cahill Tanya, Keddache Mehdi, Kallapur Suhas G, Newburg David S, Tabangin Meredith, Warner Barbara B, Jiang Xi
Abstract excerpt
OBJECTIVE: To investigate secretor gene fucosyltransferase 2 (FUT2) polymorphism and secretor phenotype in relation to outcomes of prematurity. STUDY DESIGN: Study infants were ≤32 weeks gestational age. Secretor genotype was determined from salivary DNA. Secretor phenotype was measured with H antigen, the carbohydrate produced by secretor gene enzymes, in saliva samples collected on day 9 ± 5. The optimal...
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