Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The diverse origins of circulating cell‐free DNA in the human body: a critical re‐evaluation of the literature

14 Apr 2018

Abstract excerpt

Since the detection of cell-free DNA (cfDNA) in human plasma in 1948, it has been investigated as a non-invasive screening tool for many diseases, especially solid tumours and foetal genetic abnormalities. However, to date our lack of knowledge regarding the origin and purpose of cfDNA in a physiological environment has limited its use to more obvious diagnostics, neglecting, for example, its potential utility in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Pancreatic and Hepatic Oncology Research
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29654714
DOI: 10.1111/brv.12413

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The diverse origins of circulating cell‐free DNA in the human body: a critical re‐evaluation of the literaturePMID 29654714Read ↗

Putative Origins of Cell-Free DNA in Humans: A Review of Active and Passive Nucleic Acid Release MechanismsSemantic proximity Read ↗

The emerging role of cell-free DNA as a molecular marker for cancer managementSemantic proximity Read ↗

Concentration of cell-free DNA in different tumor typesSemantic proximity Read ↗

Cell-Free DNA Fragmentomics: The Novel Promising BiomarkerSemantic proximity Read ↗

Cell-Free DNA: Features and Attributes Shaping the Next Frontier in Liquid BiopsySemantic proximity Read ↗

Origins, structures, and functions of circulating DNA in oncology.Semantic proximity Read ↗

Life and death of circulating cell-free DNASemantic proximity Read ↗

A hitchhiker’s guide to cell-free DNA biologySemantic proximity Read ↗

The role of extracellular DNA (exDNA) in cellular processesSemantic proximity Read ↗

Cell‐free DNA‐associated multi‐feature applications in cancer diagnosis and treatmentSemantic proximity Read ↗

Cell-free DNA: the role in pathophysiology and as a biomarker in kidney diseasesSemantic proximity Read ↗

Circulating Cell-Free DNA in Hepatocellular Carcinoma: Current Insights and OutlookSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.