The Challenges and Prospects of p53-Based Therapies in Ovarian Cancer.

Abstract excerpt

It has been well established that mutations in the tumor suppressor gene, p53, occur readily in a vast majority of cancer tumors, including ovarian cancer. Typically diagnosed in stages three or four, ovarian cancer is the fifth leading cause of death in women, despite accounting for only 2.5% of all female malignancies. The overall 5-year survival rate for ovarian cancer is around 47%; however, this drops to an...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mutation
• Share to Ovarian Neoplasms
• Share to Tumor Suppressor Protein p53