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Whole genome sequencing provides comprehensive genetic testing in childhood B-cell acute lymphoblastic leukaemia

19 Jan 2023

Abstract excerpt

Childhood B-cell acute lymphoblastic leukaemia (B-ALL) is characterised by recurrent genetic abnormalities that drive risk-directed treatment strategies. Using current techniques, accurate detection of such aberrations can be challenging, due to the rapidly expanding list of key genetic abnormalities. Whole genome sequencing (WGS) has the potential to improve genetic testing, but requires comprehensive...

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PMID: 36658389
DOI: 10.1038/s41375-022-01806-8

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