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Integrative genomic analysis of childhood acute lymphoblastic leukaemia lacking a genetic biomarker in the UKALL2003 clinical trial.

2022-10-18

Abstract excerpt

<title>Abstract</title> <p>Incorporating genetics into risk-stratification for treatment of childhood B-progenitor acute lymphoblastic leukaemia (B-ALL) has contributed significantly to improved survival. In about 30% B-ALL (B-other-ALL) without well-established chromosomal changes, new genetic subtypes have recently emerged, yet their true prognostic relevance largely remains unclear. We integrated next generati...

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Literature Corpus work: b8452a06-eeab-596e-abc5-d303858a5d66
DOI: 10.21203/rs.3.rs-2159503/v1

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