Article
Actionable genomic landscapes from a real-world cohort of urothelial carcinoma patients.
Urologic oncology - 1 Mar 2023
Gerald Thomas, Margulis Vitaly, Meng Xiaosong, Bagrodia Aditya, Cole Suzanne, Qin Qian, Call S Greg, Mauer Elizabeth, Lotan Yair, Woldu Solomon L
Abstract excerpt
BACKGROUND: Recent targeted therapies for advanced and metastatic urothelial cancer have generated enthusiasm, but the actionable genomic landscape of early-stage disease remains largely unknown. Here, we utilized a large, real-world cohort to comprehensively investigate the incidence of genetic alterations with potential therapeutic implications at all stages of bladder cancer. MATERIALS AND METHODS: We...
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